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Item Metadata only Effect of Hydro-Ethanol Extract of persea americana Seed on Nickel Chloride-Induced Oxidative Hepatorenal Damage in Rats(Bells University of technology, Ota, 2019-04-16) EGBOGA, Chiedozie arinze; Dr. Kazeem A. AkinwunmiNickel exposure is common and increasing evidence showed it can cause oxidative tissue damage. This has led to the search for remedy amongst antioxidant medicinal plants. In this study, the antioxidant capacity, amino acid profile and some phytochemicals in persea americana seed were determined. Additionally, effects of hydro ethanol extracts of persea americana (HEPA) on nickel chloride (NiCl2) induced oxidative hepato-renal damage were investigated and compared with H-acetylcysteine (NAC). Thirty-six rats were divided equally into six groups. Control group was given water, while test groups were treated with 10 mg/kg Nicl2, 25 mg/kg NAC and 50 mg/kg HEPA alone or in combination. HEPA and NAC were given daily for three weeks, while NiCl2 was injected once in a week before the rats were sacrificed.Item Metadata only Alkaline Phosphatase Activities and Serum Urea Levels in Albino Rats Treted with Aqueous Extracts of Psidium.(Bells University of Technology, Ota., 2009-06-11) AKINSANMI, Babajide; Mr. O. S. AdeyemiThe biochemical effect of aqueous extract of Psidium guajava leaf on some enzymes were studied in the kidney. The histopathological studies of the tissues were also carried out. The P. guajava leaf extract were administered intraperitoneally to albino rats consecutively for seven days.